Name:Sahar Mahate
Internship, Co-op or Research Site:Johns Hopkins Medicine
Position Title:Undergraduate Student Researcher
Major(s)/Minor(s):Biology and Health Administration/Policy
Current Class Level:Junior
Work Term:Summer 2020
Tell us about your internship, co-op, or research opportunity, including your day-to-day responsibilities.
As lab research shifted online, my responsibilities changed a lot. When I was working at this lab in person, I injected tumors into the tibias of live animal models, operated technology for X-rays and ultrasounds on animal models, completed stress experiments and necropsies on mice and rats, and performed western blots, cell cultures, and DNA methylation analyses. With virtual work, there was a lot more focus on literature review and data analysis. We would have meetings where research was discussed, and I would be assigned specific topics to present on. We also began using a new proteomic analysis program to identify and compare pathways of primary osteosarcoma tumors and secondary pulmonary tumors to determine how commonly upregulated pathways associated with pulmonary metastasis in osteosarcoma can be inhibited. My responsibility was to work with the other undergraduate researchers in the lab to figure out how the program worked, use it to analyze the data, and present relevant findings at lab meetings.
Describe the process of obtaining your position. When did you hear of the position and submit your application?
This is a research lab I've been working at since high school, and have continued to work with throughout college.
What have you enjoyed the most about your position or organization?
This summer, I really enjoyed being able to take charge and work on an independent project with the proteomics analysis program to contribute to the lab research. It gave me the opportunity to collaborate with other undergraduate colleagues to teach ourselves something new and to share the knowledge with the researchers in the lab, as the program was new to all of them as well.
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