The UMBC LSAMP 2022-2023 Annual Report highlights involvement in the UMBC LOUIS STOKES ALLIANCE FOR MINORITY PARTICIPATION (LSAMP) program. LSAMP participants have access to individualized advising, campus workshops, funded research experiences, and national and international conferences to strengthen their STEM identity and promote entry into top graduate programs. 

We want to specifically celebrate the achievements of those pursuing their bachelors of science in chemical engineering and the departmental faculty supporting their efforts. 

ANNUAL BIOMEDICAL RESEARCH CONFERENCE FOR MINORITIZED STUDENTS (ABRCMS) (Page 11)

Name| Major| Topic | Faculty Advisor

Evalynn Ellison | Chemical Engineering | Molecular Biotechnology | Dr. Brandon DeKosky

Ariel Wilson-Gray | Chemical Engineering | Bioengineering | Dr. Tamara Kinzer-Ursem 

SUMMER 2023 RESEARCH FELLOWSHIP PROGRAM (Page 27)

Name and Class | Major |Topic| Faculty Mentor | University

Nhyira Ghunney ‘24 | Biological Sciences | Tissue Engineering | Dr. Erin Lavik | UMBC 

Amaya Johnson ‘25 | Biological Sciences | Tissue Engineering | Dr. Erin Lavik | UMBC

CLASS OF 2023 GRADUATING FELLOWS AND POST-GRADUATION PLANS (Page 34-35)

Joana Hernandez Chemical Engineering Prospective Graduate Student

Diego Iglesias Vega Chemical Engineering Graduate Student at MIT

Rachel Myers Chemical Engineering PhD Student at Massachusetts Institute of Technology

Excerpt from:

Machine Learning for Bioprocess Sensor Innovation

By Gareth John Macdonald - January 31, 2024

Machine learning (ML) could allow drug firms to create predictive process models that optimize development, production, and quality control. But, before embracing ML on the factory floor, manufacturers will need data to “train” the computer algorithms that drive the approach. And this means having process sensors sophisticated enough to track multiple parameters in real-time in highly complex cell cultures according to an industry expert.

Machine learning is a specialized form of artificial intelligence in which computer programs learn to solve tasks or understand the dynamics of complex systems with minimal or no direction. The process is iterative, and the solutions improve over time as more data is introduced.

This need for training data is driving innovation in process sensors, says Govind Rao, PhD, who is director of the Center for Advanced Sensor Technology at the University of Maryland, Baltimore County.

“At the end of the day, AI/ML tools will allow for process monitoring to be simplified once data are generated at scale to relate process conditions to critical quality attributes. The need to run QC tests on quarantined bulk drug substance will be greatly reduced,” he explains. “However, to get there will require high-density process monitoring to allow ML/AI algorithms to relate process conditions to off-line measurements such as glycosylation, aggregation, etc.”

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National Institutes of Environmental Health Sciences highlight Professor Upal Ghosh’s work cleaning contaminated waterways

By: Catherine Meyers | Published: Feb 23, 2024 | UMBC NEWS

The positive environmental and health impacts of work led by Upal Ghosh, professor of chemical, biochemical, and environmental engineering at UMBC, was recently highlighted by the National Institutes of Environmental Health Sciences (NIEHS). The agency showcased a low-cost technology that Ghosh and his colleagues developed to clean waterways contaminated with polychlorinated biphenyls (PCBs), a group of likely carcinogenic chemicals that were used in insulation, coolants, and electrical equipment for decades before being banned in the U.S. in 1979. 

The chemicals are stable and persist in the environment, often accumulating in fish that live in contaminated waterways and posing a risk to humans who consume those fish. NIEHS funded Ghosh’s research into using activated carbon pellets to bind the chemicals in place at the bottom of the waterways. This prevents the PCBs from circulating through the aquatic food chain. In projects carried out in contaminated lakes, rivers, and harbors in Delaware, Maryland, and elsewhere, Ghosh’s team demonstrated that the technique could significantly reduce the concentration of PCBs in the water and in aquatic lifeforms. Importantly, the technique is also significantly cheaper than standard clean-up approaches, such as dredging and disposing of contaminated sediment. 

In related work performed with Kevin Sowers, from the Institute of Marine and Environmental Technology, Ghosh’s team also developed a way to combine the activated carbon with microbes that break down PCBs, reducing their toxicity.

With NIEHS support, Ghosh has co-founded two companies—Sediment Solutions and RemBac—to commercialize the technology and deploy it at full-scale to clean up contaminated sites across the country, such as at Mirror Lake in Delaware.

“The technology brings together innovations in material science and biology,” says Ghosh. It’s an honor, he says, that the NIEHS, the leading agency in the country that funds research on public health and the environment, recognized “the real impact our research is having on improving public health.”

About this book: 

University of Maryland, Baltimore County - Applying a Novel Symbolic Regression To Speed Up Surface Chemistry Simulations

As summer wildfire smoke choked Baltimore, UMBC air pollution researchers leapt into action

Starting this May, a series of wildfires in Eastern Canada sent enormous smoke clouds wafting into the U.S., triggering air quality warnings in cities from the Midwest to the Northeast. For days, orange skies backdropped landscapes clouded by acrid air. People who could hunkered inside with the doors and windows shut. Those who had to go out faced itchy eyes, burning throats, and worse.

As a resident of the Baltimore area—which was blanketed with particularly bad smoke in both early and late June—UMBC Professor Chris Hennigan looked at the haze with dismay. But as an environmental engineer who studies air pollution, he had an additional thought: “We were looking at the air quality forecasts, and we thought ‘We have to gather data,’” he says.

The public found many colorful words to describe the summer’s unwanted smoke: brutal, eerie, dystopian.

Hennigan and his team have been working to put numbers to the adjectives. On the roof of the engineering building, the researchers installed a squat, white sensor that monitors the levels of tiny particles in the air, particularly those measuring 2.5 micrometers in diameter or less—smaller than most bacteria. Called PM_2.5, these particles are released in large numbers during fires. They are dangerous to human health because they can work their way into the deepest parts of the lungs and even enter the bloodstream.

The sensor showed huge spikes in PM_2.5 when the smoke blew through, on some days reaching levels considered unhealthy for anyone to breathe.

The researchers also set up equipment to filter particles out of the air. After 24 hours, they collected the filters, which they are storing, neatly labeled, in a refrigerator in Hennigan’s lab.

The filtered samples will advance at least two ongoing investigations, Hennigan says. In one avenue of inquiry, Joel Tyson, Ph.D. ’23, biochemical engineering, is studying how tiny particles can harm human lung cells. Before this year’s smoky summer, Tyson had been studying the toxic effects of particulate matter normally found in the Baltimore air. With the new smoke samples, he will start to investigate whether wildfire smoke particles, per unit, are more toxic than regular urban particulate matter, which comes from sources such as cars and power plants. Some studies have indicated that wildfire particulate matter is indeed more toxic, but more research is needed before any definitive conclusions can be reached.

In another line of research, Hennigan is also studying how particles in the air, including from smoke, may affect the climate. Undergraduate chemical engineering students Danielle Larios ’25 and Luis Rodriguez ’25 are assisting in the investigations.

The researchers study how particles of brown-colored carbon-containing material absorb light. Burning vegetation sends large amounts of this brown carbon into the atmosphere. It’s possible that the particles are trapping significant heat from the sun, accelerating the pace of planetary warming. Such effects are not normally included in global climate models, and better understanding of the process could improve humanity’s ability to predict, and manage, the coming years of climate upheaval.

Climate change and wildfires are intimately linked. This summer was not only smoky, but also scorching. July marked the hottest month ever recorded, and scientists predict that as the world continues to warm, wildfires will continue to increase in quantity and intensity. “Smokeageddon,” as headlines put it, may become the new normal.

Hennigan says recent research illuminates how much wildfire smoke has contributed to air pollution trends. He points to a paper published in September in the scientific journal Nature that estimated that since 2016, wildfire smoke in the contiguous United States has undone around 25% of the progress in air quality made between 2000 and 2016.

For the researchers in Hennigan’s lab, those effects have been felt personally. 

Rodriguez recalled how in June he had to go out to buy a fresh pack of N95 masks. “The smoke was just awful,” he says. Larios says she felt a burning at the back of her throat in just 15 minutes walking to her car.

For Tyson, the effects of the smoke were so bad that at one point he struggled to breathe and had to visit the doctor. The episode, he says, drove home the importance of his toxicology research.

All three note both the complexity of the systems they are studying and the importance of discovering new knowledge that might help society handle the environmental challenges it faces.

“Our work can have real-world impact, and that’s exciting,” says Larios.

Description

The Department of Chemical, Biochemical, and Environmental Engineering (CBEE) at the University of Maryland Baltimore County (UMBC) seeks to fill a tenure-track position in the broad fields of biomedical or biomolecular engineering, including areas involving synthetic biology, systems biology, bioinformatics, biomanufacturing, metabolic engineering, and biological materials. We are especially interested in applicants who conduct interdisciplinary research which will complement the current expertise in our department and college.

For full details:  https://cbee.umbc.edu/facultysearch/

UMBC is an Affirmative Action/Equal Opportunity Employer. Minorities, women, veterans, and individuals with disabilities are encouraged to apply.

IFPAC has been leading the way in Advanced Manufacturing Science for over 35 years. 

The annual conference 'IFPAC 2023' held June 4-7, 2023 in North Bethesda, MD and attended by more than 400 people focused on 'A Framework for the future, advanced manufacturing quality & innovation'.

Many students presented their research during two poster sessions. UMBC graduate students mentored by CBEE faculty earned first and second places for the best student poster presentations. 

1st place winner: 

•  Vikash Kumar, Chemical and Biochemical Engineering, PhD
  Poster Title : Reinventing Shake Flask Fermentation: The Membrane Flask

2nd place winners: 

• Vida Rahmatnejad, Chemical and Biochemical Engineering, PhD;  
  Poster Title: Flow Cell: A Completely Noninvasive Monitoring System for Cell Culture Processes
• Revati Kadolkar, Chemical and Biochemical Engineering, PhD;  
  Poster Title: Application of mechanistic modelling for the understanding of tailing in high performance liquid chromatography (HPLC)