Channel is a Biochemistry and Molecular Biology major with minors in Mathematics and Sociology (class of 2018).

During my paid summer internship at the Institute for Regenerative Engineering in Farmington, Connecticut, I was at the University of Connecticut Health Center, School of Medicine in the Department of Orthopaedic Surgery. I was a participant in the Research Experience and Mentoring (REM) Program, under the instruction of Dr. Cato T. Laurencin, a recent award recipient of the National Medal of Technology and Innovation, the Nation's highest Honor for Technological Achievement.  My project focused on the Development and Characterization of Human Recombinant Lactoferrin Nanofibers as Scaffolds for Regenerative Engineering. I studied the regeneration of bone, skin and cartilage growth in-vitro and in-vivo, with electrospun nanofibers, coated in various proteins that are found in both blood, like Albumin and in bone, like Lactoferrin. I used various solvents and concentrations to create a stable nanofiber, that would induce increased Bone Cell viability and proliferation, while also activation biodegradation upon cell regeneration. For tests with cartilage and bone, I used hydro gels that were surgically implanted in mice and rats. I was able to gain a confident skill set in Cell Culturing, Cell Suspension, Immunostaining, ALZ Staining, Live/Dead staining, and with using the Scanning Electron Microscope for various imaging. I have also gained skill in using Image J analysis, FTIR analysis, Electros pinning, Titer Blue Assay, and Cross-linking. I was trained to used the Confocal Microscope, with the Velocity Imaging Program, Lab Safety, Animal Safety,  and Rat Implantation and Surgical Stitch Patterns.

How did you find the research opportunity?
I realized that I wanted to have a career in Medicinal Research and noticed that I had an interest in the Musculoskeletal System. I researched African American Cutting Edge Researchers and Dr. Laurencin popped up. I was so intrigued with his accomplishments and research projects. I just knew I needed to work under him and with him. A friend of mine pepped talked me into emailing him that night, (it was 2:00am!), because she knew I'd chicken out when the excitement ended. So, I emailed him and asked him to be m mentor. I also mentioned that I wanted to do research with him during the summer and quite honestly, to my amazement, Dr. Laurencin emailed me back in the next hour and set up a teleconference from there. The rest is history!

How did you learn what you needed to know to be successful in this project? This project has definitely taught me so much about myself and about the world of Science. My Graduate Assistant, Eric James, a recent PhD recipient, was amazing! He quickly realized that this was all new to me, but did not lighten up on his expectations. He made to teach me the reasoning and purpose behind certain research methods and topics, but also introduced me to the Medical Library, PubMed, and other various sources for additional help. Eric also cared about my critical understanding for Medical Research and understanding Medical Research Papers. During that time, there was a Cell Biology and Tissue Engineering Journal Club. Eric made sure that we attended meetings weekly and I even got a chance to present a review of a research paper. I Participated in this  journal club, that was designed to understand molecular aspects of cell biology and tissue engineering scientific literature. Presentations include “Language of Science” and “How to read and understand a science article”.

What was the hardest part about your research?The hardest part about my research would have been the numerous trials with error and repeat. Initially, it was hard dealing with that many negative results. It was quite discouraging, but Eric continued to reassure me in qualitative critic and support. I wouldn't trade those experiences for anything.It was then where I truly learned PERSERVERANCE!

What was the most unexpected thing? I did not know how much of a family a research (SQUAD) could really be. Honestly, I thought research was suppose to be sleep, lab, work, and repeat, but it wasn't, at all! This lab was amazing! My cohort and I went out to eat, to the movies, the mall and even had dinner at my house. Dr. Laurencin even invited us over his house and allowed us to get to know his family and him, in a more personal level. How cool was that?!

How does this research experience relate to your work in other classes? My research correlates to so many classes that I am taking now, for instance, toxicology, with Dr. Fishbein. We talk a lot about the toxins that can affect blood and during my experience with REM, we spoke a lot about the importance of Blood, not just in circulation, but especially for your bone health. I can also relate this course to a previous course, Organic Chemistry II, which depicts mechanisms and various conformational changes due to their affects. This was definitely practiced in lab, as I had to continue testing various solvents, at various concentrations with Albumin and Lactoferrin.

What is your advice to other students about getting involved in research? GET. IN. VOLVED. I can not express how much research really helped anchor me, as a student at UMBC. It's easy to get caught up in classes and GPA, but when you actually practice what you have always wanted to do, there is a rush that happens within you. There's a focus that comes to you. All of a sudden, things make sense. It's no longer school, because my parents say so, its school because I want to be my MENTOR!

What are your career goals? I am planning on going into the Medical Field, also studying Regenerative Engineering with Stem Cell Treatment to Bio-printed Organs and Tissues.

What else are you involved in? I am the President of United Christian Council, a member of the Retriever Leadership Institute, a Mathematics Grader/Tutor, STEM Education Advocate for students in Baltimore City, a Mentor and friend!

Have mentor-led research and want to be featured as UMBC's next Researcher of the Week? email aprilh@umbc.edu

Get ready for Critical Social Justice: Rise with our What You Need to Know series. Written by Sheila Suarez.

Activism is the action of campaigning to cause social or political change, and it takes many forms of expression; physical action, artistic expression, and academic scholarship, to name a few. The Native people of the United States have their own strong activism history with the purpose of bettering the lives of those that are part of their community.

Native peoples have been fighting for centuries since the colonization of the Americas. From receiving proper treatment from the government to accessing the land that was once where they lived, indigenous peoples have been actively fighting for respect, autonomy, and equal treatment.

Scholars consider the roots of modern Native activism begins with the Occupation of Alcatraz in 1969. The Occupation of Alcatraz was an action taken by 90 urban Native college students to occupy the island of Alcatraz. Those occupying the island demanded that the island be given back to the Native peoples of the San Francisco Bay area, eventually allowing them to create a college and culture center. After 19 months of occupying the island, the activists were forcibly removed by the United States government, but not before inspiring many others in tribal communities across the nation.

Native peoples’ activism has taken many forms since the Occupation of Alcatraz. The rise of Indigenous Peoples’ Day is a great example of this. Columbus Day, celebrated on the second Monday of October, ultimately commemorates the colonization of the Americas and the subsequent genocide of millions of indigenous lives. Indigenous Peoples’ Day was created in 1992 in Berkeley, California as an alternative to Columbus Day. Through the legal action of Native American leaders, this holiday is meant to be a celebration of the Native Peoples, their history, and their resilience. Slowly but surely, many different cities and townships have adopted the new holiday.

When thinking about Native activism, many may also look to the recent efforts to halt the Dakota Access Pipeline. The Standing Rock Sioux and the Cheyenne River Sioux were the first to oppose the construction of the Dakota Access Pipeline (DAPL). In addition to legal battles, there was an incredible presence on the ground; peaceful protest happened 24/7 throughout the spring, summer, fall, and winter of 2016. Native activists, like our keynote speaker Dr. Adrienne Keene, came together in solidarity with environmentalists and many others to challenge the construction of DAPL and educate other communities on how this 1,100 mile long oil pipeline could poison the drinking water of the Native peoples in Standing Rock and other communities that lived along its path. It was, however, not only the threat of environmental degradation but the continued exploitation of Native lands by the U.S. government and corporate interests that many opposed. As legal battles ensued, the peaceful protesting around construction sites swelled to thousands, and just so, North Dakota police began to use tear gas, rubber bullets, water spraying, dogs, and other violent tactics to suppress protesters. Unfortunately, in January 2017, President Trump signed an executive action to advance the construction of DAPL. Protesters continued to seek legal protection and stays, but were ultimately booted out by police in February of this year.

The history of Native activism is a lesson in resistance and resilience. As a group that has had to fight for their rights, culture, and land for hundreds of years, their sustained commitment is a testament to the strength and power of their people and communities. Although we have only touched the surface of this history, we look forward to learning more.

If you would like to learn more about Native activism, come hear Adrienne Keene speak about Native appropriations and Indigenous social media, Tuesday, October 24, 2017 in the UC Ballroom from 6:00 pm to 8:00 pm. In the mean time, take a look at Adrienne Keene’s blog, Native Appropriations, as well as her active Twitter feed @NativeApprops.

Further reading below:

• Zinn Education Project’s Timeline of Native American Activism
• Adrienne Keene’s #NoDAPL: Updates, resources, and reflections
• Stand with Standing Rock News
• Standing Rock timeline from Mother Jones
• Standing Rock And The Forgotten History Of Native American Activism by Ben Railton (more on early Native American Activism)
• Indian Country Today – Native American news source

Eminent Speaker Peter J. Buxtun

“The Tuskegee Syphilis Study”